Wednesday, September 24, 2008

Ecstasy

Abuse of ketamine (pronounced Kee-ta-meen) goes hand in hand with gamma hydroxy butyrate (GHB) and MDMA (Ecstasy). Where you find one, you will likely find the others. All three are very popular with the RAVE party crowd. Ketamine hcl, a cat tranquilizer and the most commonly used anesthetic in the Vietnam War, is also used in sexual assault on occasion since it puts the victim in a frozen state for at least a brief period of time. It was big in the 70’s with New Age types like Dr. John Lilly (the model for the William Hurt character in the movie Altered States) and Timothy Leary.In order for a vial of ketamine to be in an abuser’s hand, someone has already smuggled it in from Mexico or robbed or burglarized a vet clinic or pharmacy, or in some other manner diverted the product for illicit use. In spite of that fact, ketamine is a Schedule III Controlled Substance. It should more appropriately be a Schedule II substance so that doctors and vets have to control their inventory of ketamine and provide security for it. Ketamine is essentially a less-potent version of PCP. While ketamine and GHB and MDMA provide out of body experiences and whack reality quite a bit, it is still a bit below the out-to-lunch level of PCP trips. But, of course, that varies with the amount taken and other drugs combined with it. And, flashbacks from ketamine are common.
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First, ketamine is in current use as both a veternary and ahuman anesthetic. It is called "dissociative" in action, whichmeans that the mind is "separated" from the body. In manycases, this separation results in profound hallucinations andthe sensation of entering another reality. In human use, abenzodiazapine like Versed is generally used along withketamine to induce amnesia concerning the "emergencereactions".The most easily obtained reference about ketamine isthe Physicians Desk Reference. Under the heading "Ketalar",this gives a great deal of information about the drug. Ofcourse, since this is a general medical reference, much of theinfo of interest to mind-l is not present, but it should beread anyway. Perhaps the most important property of ketamine is that,despite the induction of both anesthesia and dissociation, thecough and gag reflexes *USUALLY* are not affected. This meansthat, contrary to most other agents which will produceanesthesia and/or unconsciousness, it is very unlikely that aperson using ketamine will aspirate their own saliva and otherexcretions. This is *NOT* guarenteed, but is a pretty goodbet. Solo use, however, remains dangerous.Ketamine is generally available for non-medical uses asketamine hydrochloride. Some major chemical houses carry it ata cost of about $10/gm. I don't know if there are othersources which are cheaper, or if the veterinary form is easilyavailable. Dosages are discussed in the PDR, but are generally in therange of 100-500 mg. Conventional useage is intravenous orintramuscular, but "recreational" use is apparently more oftenthrough insufflation (snorting) or solution ingestion. Theselatter approaches are probably only effective with thehydrochloride form, but the reported doses are similar to theconventional medical doses. If this is you go seek medical help!

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